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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3B All Species: 20.61
Human Site: S814 Identified Species: 34.87
UniProt: Q7Z3V4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z3V4 NP_569733.2 1068 123070 S814 H H H S V F Y S S V D E L P S
Chimpanzee Pan troglodytes XP_509354 1068 122921 S814 H H H S V F Y S S V D E L P S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543437 1068 123121 S814 H H H S I F Y S S V D E L P S
Cat Felis silvestris
Mouse Mus musculus Q9ES34 1070 122743 S816 H H H S V F Y S S V D E L P S
Rat Rattus norvegicus NP_001137366 1070 122598 S816 H H H S V F Y S S V D E L P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423951 837 96057 L588 F Y S S V D E L P S L D S E F
Frog Xenopus laevis Q6DCL5 944 106566 V693 A L Y H R Q L V N I Y F T R S
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 Y516 M A V F H G H Y I D G G F T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVI3 1007 114856 G756 A G M A V Y H G K L L D A F F
Honey Bee Apis mellifera XP_392283 1063 121439 S809 Q T G G A L Y S W L D E L A S
Nematode Worm Caenorhab. elegans NP_499392 1066 120863 D815 S H R L C A F D E L S Q L D P
Sea Urchin Strong. purpuratus XP_786887 582 66877 L333 L Y S P I D E L P S L D K E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWB8 1029 117643 L767 F F H F L G S L L A K A M F E
Baker's Yeast Sacchar. cerevisiae P53119 910 105547 I661 C L Y E H V L I D V S F A D F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 N.A. 96.5 N.A. 92.1 91.8 N.A. N.A. 68.6 20.8 22.8 N.A. 20.4 51.5 37.6 37.1
Protein Similarity: 100 98.9 N.A. 98.5 N.A. 96 96.1 N.A. N.A. 74 40.1 38.4 N.A. 37.1 69.1 58.4 44.9
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 100 N.A. N.A. 13.3 6.6 0 N.A. 6.6 40 13.3 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 26.6 26.6 6.6 N.A. 40 46.6 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. 28.7 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. 48.7 42 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 0 8 8 8 0 0 0 8 0 8 15 8 0 % A
% Cys: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 15 0 8 8 8 43 22 0 15 0 % D
% Glu: 0 0 0 8 0 0 15 0 8 0 0 43 0 15 8 % E
% Phe: 15 8 0 15 0 36 8 0 0 0 0 15 8 15 22 % F
% Gly: 0 8 8 8 0 15 0 8 0 0 8 8 0 0 0 % G
% His: 36 43 43 8 15 0 15 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 15 0 0 8 8 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 8 0 8 0 0 % K
% Leu: 8 15 0 8 8 8 15 22 8 22 22 0 50 0 15 % L
% Met: 8 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 0 0 0 15 0 0 0 0 36 8 % P
% Gln: 8 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 0 8 0 8 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 8 0 15 43 0 0 8 43 36 15 15 0 8 0 50 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 0 0 8 8 0 % T
% Val: 0 0 8 0 43 8 0 8 0 43 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 15 15 0 0 8 43 8 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _